Herpes is a very common infection caused by HSV-1 and HSV-2. Approximately a third of the world’s population aged 0–49 have oral herpes, and half a billion have genital herpes. According to the Centers for Disease Control and Prevention (CDC), many with herpes are unaware they have an infection, with an estimated 87.4% aged 14–49 going undiagnosed.¹ ²
Herpes can cause cold sores around your mouth and painful blisters around your genitals. While we don’t yet have a cure for this infection, you can take steps to avoid your risk of contracting or spreading the highly contagious virus. Let’s find out more.
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Herpes is a viral infection that is highly contagious and usually spread through direct skin-to-skin contact. Herpes simplex virus causes herpes infections. There are two types of the virus: HSV-1 and HSV-2. HSV-1 typically causes cold sores, while HSV-2 typically causes genital herpes.
Other herpesviruses, such as the varicella-zoster virus, can cause different infections in humans, such as chickenpox and shingles.
Herpes outbreaks may make your skin feel sensitive and swollen. You may experience aches in the muscles surrounding the infected area.
The symptoms of herpes may not be visible, so you may not realize you have it if the symptoms are mild. That is one of the reasons it is so easy to transmit the virus.
HSV-1 may not result in symptoms at all, but it can lead to cold sores around the mouth and lips or possibly a sore inside the mouth. These sores may hurt when you eat, tingle, sting, or burn. During the initial outbreak, you will likely experience flu-like symptoms. Cold sores typically heal in a few weeks, although you may have another outbreak a few weeks later. You may also go years before having another one.
One of the most obvious signs of genital herpes caused by HSV-2 is clusters of small blisters. They can come up in various areas, including on and around the:
Vulva
Vagina
Cervix
Testicles
Penis
Buttocks
Anus
Thighs
Blisters can break and turn into sores that cause itchiness, pain in the genital area, and difficulty urinating.
During your first herpes outbreak, you may feel like you're coming down with the flu. You may notice symptoms like:
Headaches
Feeling tired
A fever
Swollen glands in your throat, in your armpits, and near your groin
Genital herpes can develop from HSV-1, which may be passed from the mouth to the genitals during oral sex. An HSV-1 infection can mimic an HSV-2 infection, and you can experience multiple symptoms at once.
The herpes simplex virus can be transmitted through skin-to-skin contact and vaginal, oral, or anal sex. It's also possible to get an infection from an object contaminated by someone with the disease that comes in contact with your skin.
Risk factors include:
Unprotected sex, although a condom/dental dam may not cover all sores
Sexual activity with multiple partners
Having sex with someone who isn’t taking antivirals to limit outbreaks
Being in a certain population group:
Women who have sex with men: HSV spreads more easily from men to women than from women to men.
Men who have sex with men
People with a history of sexually transmitted diseases
Older adults
Black people in the US
If you’re concerned about your herpes risk, speak to your doctor for advice.
The symptoms of herpes can include:
Blisters or a rash on or near the mouth or genitals
Swollen glands in the groin area
A fever over 101 degrees Fahrenheit
Flu-like symptoms
It's not always possible to identify that someone has herpes just by looking at them, but these symptoms may indicate an infection is present.
Cold sores often come with their own symptoms, including:
Pain around the infected area Tingling sensations before developing into blisters
Redness on or around the lips or face
Fever
Sore throat
Headaches
Pimples and herpes blisters may look similar, but they form because of different causes. Pimples form when excess sebum combines with dead skin cells to clog pores. They can appear on any part of the body and aren't contagious.
Herpes blisters are white, yellow, or red translucent sores or bumps filled with a clear liquid, while pimples are opaque with a yellow or white head.
Herpes can be difficult to diagnose because not everyone with it will experience symptoms. Current tests are most accurate when symptoms are present. A doctor can diagnose herpes simply by examining the blisters or sores and confirming it by performing a swab test of sores that have not fully healed.
Doctors rarely use blood tests because they have limitations. Speak to your healthcare provider about whether a blood test would be useful to confirm your diagnosis.
Treatments that reduce the severity, frequency, and duration of outbreaks include antivirals like valacyclovir, acyclovir, or famciclovir.
You can apply topical numbing agents like lidocaine cream or benzocaine gel during an outbreak to ease the pain.
Even if you have no visible symptoms, it's important to take precautions by practicing safe sex and always using protection during sex, including oral sex.
During an outbreak, it’s vital to do everything you can to avoid spreading the virus. That means:
Avoid kissing and oral sex to prevent spreading the virus during an oral herpes outbreak
Abstain from sex during a genital herpes outbreak
Avoid touching open sores to reduce the risk of spreading them to other parts of the body
Never pop the sores
Avoid peeling scabs, as this prolongs the healing process
Wash your hands with soap and water before and after applying an ointment to your sore
Don’t share any products you use on your lips or sores during a flare-up
Don’t share towels, dishes, or cutlery
Don’t kiss infants: Neonatal herpes infection in babies can be deadly
While there is no known cure for herpes, you can prevent an outbreak. You can take antiviral medications like acyclovir and learn about your triggers.
While scientists aren’t exactly sure what can trigger an outbreak, these can cause flare-ups:
Stress
Menstruation (periods)
Another infection or illness, such as a cold
Fever
Sunlight exposure
Tiredness
Injury to the area
Hot or cold temperatures
If you suffer from recurrent outbreaks of genital herpes, your doctor may suggest taking an antiviral every day to prevent future outbreaks and transmission. These drugs prevent HSV from multiplying in your body's cells.
Call your doctor if:
You're pregnant
You have a high fever
You’re vomiting
The sores aren’t healing
It's important to see your physician if you're concerned about herpes and need some clarification on the infection.
Your doctor will want to confirm you have symptoms of herpes rather than an infectious disease like chickenpox. While there’s no cure, your doctor may prescribe acyclovir to control the outbreak.
HSV-1 and HSV-2 are two similar herpes simplex viruses that cause herpes. Outbreaks may lead to flu-like symptoms, including chills, fever, body aches, and headaches. While there isn't currently a cure for this virus, medications can manage symptoms and reduce outbreaks. Speak to your doctor for diagnosis and their recommendations for treatment.
The only way to know for sure is to ask your doctor or healthcare professional. Your doctor may be able to tell from looking at the blisters. They can also check by swabbing the existing sores or ordering a blood test, although testing is not always required.
An outbreak of cold sores or genital herpes usually looks like a cluster of fluid-filled blisters that can burst and crust over.
There isn't one specific cause for an outbreak after contracting HSV. Outbreaks are unpredictable, but contributory factors include stress, lack of sleep, or other illnesses that cause a weakened immune system.
Sources
Massive proportion of world’s population are living with herpes infection | World Health Organization
Genital herpes – CDC detailed fact sheet | Centers for Disease Control and Prevention
Other sources:
Herpes simplex virus | World Health Organization
Chapter 68 herpesviruses (1996)
Genital herpes treatment and care | Centers for Disease Control and Prevention
Genital herpes screening FAQ | Centers for Disease Control and Prevention
Abreva | Rx List
Genital herpes | Centers for Disease Control and Prevention
Oral & genital herpes | Planned Parenthood
We make it easy for you to participate in a clinical trial for Cold sores, and get access to the latest treatments not yet widely available - and be a part of finding a cure.