Blood Disorders Clinical Trials

Haemophilia is a genetic disorder in which the blood doesn’t clot properly. This is due to it not having enough clotting factor – a protein in the blood that controls bleeding.

With von Willebrand Disease, people have a problem with a protein in their blood that helps control bleeding – the von Willebrand factor. The protein doesn’t work the way it should, or people do not have enough of it. The result? Blood takes longer to clot, and bleeding takes longer to stop. 

Hepatitis C is a liver infection caused by the hepatitis C virus. It’s transmitted through blood-to-blood contact and can cause long-term health problems if left untreated.

HIV (human immunodeficiency virus) is where a virus attacks cells that help the body fight off infection. This makes those with HIV more vulnerable to other infections and diseases. Untreated HIV can lead to AIDS (acquired immunodeficiency syndromes).

Symptoms for bleeding disorders vary depending on the condition. 

Haemophilia symptoms include unexplained and excessive bleeding from cuts, injuries, or surgeries; numerous large or deep bruises; unusual bleeding after needles; painful, tight joints; blood in urine or stool; random nosebleeds and more.

Von Willebrand Disease shares some symptoms with haemophilia, including large and frequent bruises; heavy or long-lasting bleeding from cuts, injuries or surgeries. 

People with VWD also may have bleeding gums; women may have heavy periods or experience heavy bleeding in labour; long-lasting nosebleeds; and some people may bleed into joints, muscles, and into the gut.

Symptoms of Hepatitis C include bleeding and bruising easily; fatigue; poor appetite; jaundiced skin; itchy skin; fluid buildup in the abdomen; swelling in the legs; slurred speech and more.

Two-thirds of people who get infected with HIV will experience a flu-like illness two to four weeks afterwards. Symptoms can include fever; chills; rash; night sweats; mouth ulcers; fatigue and more.

Specialised treatment is required for haemophilia, to help the blood clot normally. It is often infused or injected into a vein.

Treatment for von Willebrand Disease depends on the type the person has, and how severe it is. It may include doses of the synthetic hormone, desmopressin; injections of clotting factors; oral medications; fibrin glue and more.

95% of Hepatitis C cases are curable, thanks to new breakthrough hep C treatments (most often oral medications).

People with a positive HIV diagnosis can take antiretrovirals as treatment. PrEP, pre-exposure prophylaxis, protects HIV negative people and prevents HIV infection. Treating HIV earlier is key.

Haemophilia and von Willebrand Disease do not currently have a cure.

95% of Hep C cases are curable.

HIV is currently not curable but is well manageable.

A clinical trial is a scientific study involving patient or non-patient (healthy) human volunteers. They help determine whether medicines are safe and effective to introduce as new treatments for a particular disease or condition. 

HealthMatch matches you to clinical trials, in an easy-to-understand process. 

After completing a medical questionnaire, our platform searches for and filters eligible trials for you. You’re able to view matches and apply for trials, on your trial dashboard. 

We’ll put you in direct contact with the trial group once you’ve been accepted. We won’t stop searching until we’ve found you the right match.